Resection of colorectal liver metastases: current perspectives.
نویسندگان
چکیده
BACKGROUND Metastases to the liver is the leading cause of death in patients with colorectal cancer. METHODS The authors review the data on diagnosis and management of this clinical problem, and they discuss management options that can be considered. RESULTS Complete surgical resection of metastases from colorectal cancer that are localized to the liver results in 5-year survival rates ranging from 26% to 40%. CONCLUSIONS By adding modalities such as targeted systemic therapy and other "local" treatments for liver metastases, further gains in survival are anticipated.
منابع مشابه
Resection of liver metastases: state of the art.
In this article, we present current surgical perspectives on the management of liver metastases, with a focus on state-of-the-art resection, by drawing on clinical data provided in the medical literature. Metastases from colorectal cancer are the most amenable to resection, when considering long-term benefits. To highlight the evidence-based rationalefor surgical resection, a succinct compariso...
متن کاملRole and limitations of laparoscopic liver resection of colorectal metastases.
BACKGROUND The current experience of laparoscopic liver resection is reviewed focusing on the role and limitations of resection of colorectal metastases. Surgical technique, outcome, and the main controversies regarding the procedures are described. METHODS Current literature on laparoscopic liver resection is reviewed based on reports identified following a specified PubMed search. RESULTS...
متن کاملCurrent Management of Colorectal Cancer with Liver Metastasis
Colorectal cancer is a worldwide public health problem. More than 20% of patients with colorectal cancer present at an advanced stage, and the liver is the most common site of metastases. More recently, selection criteria for resectability have been expanded, but definition of resectability still remains challenging. Since the presence of metastases is the most relevant prognostic factor, surgi...
متن کاملColorectal cancer with Synchronous liver-limited Metastases: the protocol of an Inception Cohort study (CoSMIC)
INTRODUCTION Colorectal cancer is the fourth most common cancer in the UK and an important cause of cancer-related death. In 20% of patients, there is metastasis to the liver or beyond at the time of diagnosis. The management of synchronous disease is complex. Conventional surgery removes the colorectal primary first, followed by chemotherapy, with resection of liver metastases as a final step....
متن کاملThe evolution of liver-directed treatments for hepatic colorectal metastases.
The liver is the most common site of metastases from colorectal cancer. Over the past 3 decades, surgical resection has proved to be the most effective and potentially curative therapy for such metastases. This article will review the current practice of hepatic resection for colorectal liver metastases, including the possibility of combined resection of hepatic metastases at the time of resect...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Cancer control : journal of the Moffitt Cancer Center
دوره 13 1 شماره
صفحات -
تاریخ انتشار 2006